💊 Can You Mix Tylenol and Motrin?

Safe alternating guide for children

✅ Short Answer

Yes, you can alternate them, but it's not usually necessary and increases the risk of dosing errors. Try one medication first.

⏰ How to Alternate Safely

If one medication isn't controlling the fever, you can alternate:

TimeMedication
8:00 AMTylenol (acetaminophen)
12:00 PM (4 hrs later)Motrin (ibuprofen)
4:00 PM (4 hrs later)Tylenol
8:00 PM (4 hrs later)Motrin
⚠️ Important rules:
  • Wait at least 4 hours between ANY doses
  • Don't give Tylenol more than 5 times in 24 hours
  • Don't give Motrin more than 4 times in 24 hours
  • Keep a written log to avoid confusion

🚫 When NOT to Alternate

💡 Better Approach

Try this first:
  1. Give Tylenol OR Motrin (not both)
  2. Wait the full 4-6 hours
  3. If fever returns before that, use comfort measures (light clothing, fluids, lukewarm bath)
  4. Only alternate if single medication isn't controlling high fever

❓ FAQs

Can I give them at the same time?

Some doctors say it's safe, but there's no proven benefit over alternating. Stick to alternating if needed.

Which one should I start with?

Either works. Motrin may last longer (6-8 hrs vs 4-6 hrs) and is better for pain/inflammation.

What if I lose track of what I gave?

Wait 6 hours to be safe, then give either one. Keep a written log going forward.

🧮 Calculate Exact Doses

Get accurate Tylenol and Motrin dosing by weight

Go to Calculator

Related Articles:

→ Tylenol Vs Motrin Fever → Fever In Children Guide → Child Vomited Medicine